Explanation

A polymer formed by dehydration and condensation of aromatic dicarboxylic acids. For example, binary acids are synthesized from trans 4-hydroxycinnamic acid and 1,8-dibromooctane, and then dehydrated to form polyanhydrides. The biodegradation of polyanhydride is surface corrosion degradation, which is very valuable in the application of drug release system, and can realize the short-term constant rate release of bioactivity substances. Its surface etching degradation performance can be controlled by changing the main chain structure of polymer. The polyanhydride obtained from the condensation of bis (p-carboxyphenyloxy) methane has a fast hydrolysis rate and can be made into fibers for drug release carriers. Its corrosion rate in vivo is slightly higher than that in vitro buffer, and its release behavior is close to zero order.

Classification