Explanation

The ability of biomedical materials to cause appropriate host response and produce effective effects in specific applications. biocompatibility characterizes the biological properties of biomedical materials and is determined by the interaction between materials and living systems. This interaction includes two aspects: one is host response, that is, the effect of materials on living systems or the reaction of living systems to materials, including local and systemic reactions, such as inflammation, cytotoxicity, hemolysis, irritation, sensitization, carcinogenesis, mutagenesis, teratogenicity and immunity, which may lead to toxic and side effects on the body and rejection of the body to materials; The second is materials response, that is, the action of living systems on materials or the reaction of materials on living systems, mainly from the corrosion and degradation of materials by the biological environment, which may degrade or even destroy the properties of materials i. biocompatibility is a characteristic that biomedical materials must have, which is different from other functional materials. It is affected by many factors. The influences from materials include: materials type and shape, surface and composition, physical, chemical and mechanical properties, etc. In terms of biological systems, there are: animal species, plant site, receptor status, survival time, and usage environment. The biocompatibility of biomedical materials is closely related to their use purposes and conditions, and can be divided into Wood compatibility and histocompatibility. In recent years, biocompatibility evaluation has developed from the overall and organizational levels to the cellular and molecular levels. The research of biocompatibility involves comprehensive factors of multidisciplinary intersection, which is very complex. It is also the subject of biomedical materials.

Classification