Explanation

A type of substance that is hydrophilic and can be swelled by water but does not dissolve in water. hydrogel has three-dimensional network structure? It can swelling in water until the equilibrium volume still keeps its shape. The common ones are macromolecule hydrogel, self-assembly polypeptide gel, etc. macromolecule hydrogel can be divided into natural polymer hydrogel and synthetic macromolecule hydrogel. The former is like calcium ion crosslinking alginate, and the latter is like crosslinking polymethacrylic acid 2-hydroxyethyl ester and polyisopropylacrylamide. The hydrophilicity of hydrogel comes from the hydrophilic group W in the structure; Insolubility and swelling shape stability are caused by intermolecular forces such as chemical bonds in crosslinking molecules and hydrogen bond in self-assembly gel. hydrogel contains a lot of water. It can make the low molecular weight substances dissolved in it permeate and diffusion. Some hydrogel also have stimuli-responsive, shrinking or swelling with the change of temperature, pH value, light, electricity and other environmental parameters. Is hydrogel widely used in biomedical field? It can be used as materials for diagnosis, treatment and implantation. Diagnostic water gel mainly includes various catheter, enzyme immunoassay carriers, etc; In terms of treatment, it is mainly used as adsorbent coating, dialysis membrane, contact lenses, burn dressing, drug release carrier, etc. in hemoperfusion; hydrogel implantation include intraocular lens, artificial cornea, soft tissue substitutes, etc.

Classification