Explanation

The treatment method of separating plasma containing toxins or pathogenic substances from whole blood. It can eliminate pathogenic factors such as autoantibodies, immune complexes, immunoglobulins, cholesterol related lipoproteins, and metabolic toxins from the patient's blood. Technology can be divided into centrifugation and membrane separation. The former is to separate the main blood components (plasma and blood cells) according to the different density of the blood components, centrifugate at a certain speed, use their different sedimentation rates, discard the plasma containing toxins, and transfuse blood cells back into the patient's body. Membrane separation is to use hollow fiber membranes with different pore diameters to filter substances (mainly poisons) through the membrane, retain the useful components in the blood, and return blood cells and proteins with large molecular weights to the body. Other membrane materials include cellulose acetate, polyacrylonitrile and polymethyl methacrylate. Membrane separation method is currently the most widely used method in clinical practice. It is mainly applied to two major categories of diseases: immune and metabolic diseases, involving multiple fields such as nerves, blood, metabolism, skin, rheumatism, kidneys, and even in recent years, IH has been used in sepsis and multiple organ failure. Although there are many advantages in application, it is necessary to supplement plasma replacement solution, which increases the cost and probability of infection.

Classification