The method of separating macromolecule (protein, polysaccharide, etc.) and small molecule (amino acid, glucose, etc.) in blood through a semipermeable membrane. It is a commonly used and mature method for treating acute renal failure and end-stage renal disease. Using Donnan's membrane balance principle, the patient's blood and dialysate were introduced into the dialyzer at the same time, with reverse flow on both sides of the dialysis membrane. With the aid of the gradient of solute concentration, osmotic pressure and water pressure on both sides of the membrane, toxins are removed through diffusion and convection. At the same time, excessive water is discharged from the body through ultrafiltration and osmosis, and then the needed substances are supplemented to adjust the elonrolyte and acid-base balance. hemodialysis can partially replace the excretion and detoxification functions of normal kidneys, but has no secretion and metabolism functions.
Biomedical materials -> Blood purification materials