Explanation

It is a new discipline combining cell biology and materials engineering to construct tissues or organs in vitro or in vivo. Its basic principle is to apply the principles and methods of engineering and life science to understand the structure function relationship between normal and diseased tissues of mammals, and to develop biological prosthesis for repairing, maintaining and improving tissue functions. The basic approach is to obtain a small amount of living tissue from the body, isolate functional cells from the tissue, and culture and expand them in vitro, and then combine them with three-dimensional stem materials composition to implantation into the lesion or defect in the body. The stem is gradually degradation and absorbed in the body, and the implantation cells proliferate and secrete extracellular matrix in the body, finally forming the required tissues or organs to achieve the purpose of wound repair and functional reconstruction. There are three basic elements: stem, cell and signal system. It is considered a new milestone in the history of life science development, following cell biology and molecular biology, and also a profound medical revolution. The emergence of tissue engineering means that the development of surgery has entered a new stage of "regenerative medicine" from tissue resection, repair and replacement, which is expected to realize the regeneration and repair of diseased and defective tissues.

Classification