Provide support for cell implantation or inoculation in tissue engineering construction to form three-dimensional tissue structure. Whether in vivo or in vitro, the structure of stem is crucial to reshape the internal environment and thus affect the microenvironment of cells themselves. In order to achieve the purpose of tissue reconstruction, stem must meet some specific requirements. First of all, the stem must have high porosity and sufficient pore size to promote cell inoculation, while facilitating the diffusion of cells and nutrients in the entire stem structure. Secondly, the biological degradation of stem is also a crucial factor. The ideal stem should not be taken out by additional surgery, but can gradually degradation in the body and be absorbed by surrounding tissues. At the same time, the speed of degradation of stem should also be consistent with the speed of tissue formation, which means that the stem can maintain its structural integrity during the formation of tissue structure of seed cells. When a new tissue structure is formed, The stem will be degradation, and the newly formed tissue will replace the original stem to provide mechanical support. With the introduction of tissue induction of materials, it is hoped that they can interact with organisms to achieve the biological function of inducing tissue regeneration.
Biomedical materials -> Materials for tissue engineering and regenerative medicine